Principles of Medical Biochemistry condenses the information you need into a comprehensive, focused, clinically-oriented textbook. Drs. Gerhard Meisenberg and William H. Simmons covers the latest developments in the field, including genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, and more. An updated and expanded collection of figures and access to the fully searchable text, USMLE test questions, clinical case studies, more online at www.studentconsult.com make this the ideal resource for understanding all aspects of biochemistry needed in medicine. Access the fully searchable text online at www.studentconsult.com, along with downloadable illustrations, 150 USMLE-style test questions, 20 clinical case studies, chapter summaries, and integration links to related subjects. Understand biochemistry, cell biology, and genetics together in context through an integrated approach. Get only the information you need for your course with comprehensive yet focused coverage of relevant topics. Review and reinforce your learning using the glossary of technical terms, highlighted in the text and with interactive features online. Tap into the most up-to-date coverage of new developments in genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, RNA interference as a mechanism both for regulation of gene expression and for anti-viral defense, and more. Gain a clear visual understanding through new and updated figures that provide current and relevant guidance. Make the link between basic science and clinical medicine with new Clinical Example boxes in nearly every chapter. Focus on the most essential biochemistry principles and how they apply to clinical medicine

Ch. 1 Introduction to biomolecules 3 Ch. 2 Introduction to protein structure 19 Ch. 3 Oxygen transporters : hemoglobin and myoglobin 33 Ch. 4 Enzymatic reactions 43 Ch. 5 Coenzymes 61 Ch. 6 DNA, RNA, and protein synthesis 71 Ch. 7 Viruses 103 Ch. 8 The human genome 119 Ch. 9 Protein targeting 143 Ch. 10 Introduction to genetic diseases 153 Ch. 11 DNA technology 169 Ch. 12 Biological membranes 199 Ch. 13 The cytoskeleton 217 Ch. 14 The extracellular matrix 233 Ch. 15 Plasma proteins 255 Ch. 16 Extracellular messengers 287 Ch. 17 Intracellular messengers 313 Ch. 18 Cellular growth control and cancer 335 Ch. 19 Digestive enzymes 363 Ch. 20 Introduction to metabolic pathways 371 Ch. 21 Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation 377 Ch. 22 Carbohydrate metabolism 407 Ch. 23 The metabolism of fatty acids and triglycerides 429 Ch. 24 The metabolism of membrane lipids 447 Ch. 25 Lipid transport 461 Ch. 26 Amino acid metabolism 479 Ch. 27 Heme metabolism 503 Ch. 28 The metabolism and purines and pyrimidines 511 Ch. 29 Vitamins and minerals 523 Ch. 30 Integration of metabolism 549