The fourth edition of this volume presents entirely new material on the issue of virulence mechanisms in a ground-breaking overview of the latest knowledge. Internationally recognized authorities explain the wide variety of mechanisms used by bacterial pathogens to cause disease, and then summarize proven strategies for overcoming bacterial virulence mechansims.

I Virulence Genes by Minion, F. Chris and Cornick, Nancy 1 Type III Secretory Proteins in Pseudomonas aeruginosa by Hiromi Sato and Dara W. Frank 3 2 Identification and Characterization of Small Noncoding RNAs in Bacterial Pathogens by Jonathan Livny and Matthew Waldor 23 3 Pathogenesis of Mycobacterium tuberculosis by Michelle H. Larsen and Dee N. Dao and Anthony D. Baughn and Kripa Jalapthy and William R. Jacobs, Jr. 31 4 Integration of Capsular Polysaccharide Biosynthesis with Metabolic and Virulence Pathways in Streptococcus pneumoniae by Janet Yother 51 II Microbial Interactions in Health and Disease by Stanton, Thaddeus B. 5 The Role of Bacteriophage in Group A Streptococcal Pathogenesis by Vincent A. Fischetti 69 6 Regulatory Networks in Pathogenic Bacteria: Lessons from Cell-Cell Communication in Pseudomonas aeruginosa by Martin Schuster and E. P. Greenberg 75 7 Coaggregation and Distance-Critical Communication by Paul E. Kolenbrander and Nicholas S. Jakubovics and Natalia I. Chalmers and Gilad Bachrach 89 8 Commensal Bacteria in Health and Disease by Harry J. Flint and Petra Louis and Karen P. Scott and Sylvia H. Duncan 101 9 Free-Living and Host-Associated Protozoa as Training Camps for Intracellular Pathogens by Steve A. Carlson and Sharon K. Franklin and Mark A. Rasmussen 117 III Bacterial Attachment, Invasion, and Colonization by Zhang, Qijin 10 Mycoplasma pneumoniae Attachment and Colonization of the Respiratory Mucosa by Duncan C. Krause and Jarrat L. Jordan and How-Yi Chang and Hyun Kyung Park and Thomas M. Krunkosky 135 11 Gender Differences in Neisseria gonorrhoeae Pathogenesis by Jennifer L. Edwards 149 12 Escherichia coli at the Intestinal Mucosal Surface by Tyrrell Conway and Paul S. Cohen 175 13 The Role of Flagella in Campylobacter Virulence by Patricia Guerry 197 IV Bacterial Effects on Host Cells by Nolan, Lisa More...