The second edition of Osteoporosis in Clinical Practice provides a concise review of the current knowledge of osteoporosis. It is aimed at the busy practitioner who is increasingly involved in the management of osteoporosis and who wants accurate and practical answers to questions that arise in daily clinical practice. All the major aspects are covered including diagnosis, fractures, prevention and treatment. Concise chapters have been written by recognised experts in the area providing the reader with the most up-to-date and authoritative knowledge on each of the topics discussed. This makes the book an invaluable source of reference for those in primary care who are increasingly having to deal with patients with osteoporosis in their daily clinical practice. A must-have for every clinician treating patients with osteoporosis. It gives the latest information on diagnosis and treatment, founded on evidence-based medicine.

Contributors Abbreviations Introduction : general outlines of assessment and management of osteoporosis : postmenopausal osteoporosis as an example Pt. 1 General aspects of bone, osteoporosis and fractures 1 Normal skeletal structure and function 3 2 Physiology of calcium homeostasis and bone remodeling 9 3 Biomechanics of bone and fracture 15 4 Pathophysiology of fractures 21 5 Epidemiology of osteoporotic fractures 29 6 Socioeconomic impact 39 Pt. 2 Investigations in osteoporosis 7 Bone densitometry, radiography, and quantitative ultrasound for the diagnostic assessment of osteoporosis 47 8 Biochemical indices of bone turnover 59 9 Dual energy X-ray-based absorptiometry in daily clinical practice 69 10 Differential diagnosis : back pain and osteoporosis 75 11 Differential diagnosis : bone pain and fractures 87 12 Falls in older people 93 13 Genes and osteoporosis 101 Pt. 3 Treatment of postmenopausal osteoporosis 14 Prevention early after menopause 111 15 Pharmacologic and non-pharmacologic strategies to prevent hip fracture in old age 119 16 Selective estrogen receptor modulators 129 17 Bisphosphonate therapy for postmenopausal osteoporosis 133 18 Anabolic drug therapy in osteoporosis 143 19 Surgical therapy of fractures 147 Pt. 4 Other aspects of osteoporosis 20 Osteoporosis in men 155 21 Corticosteroid osteoporosis 163 22 Tumor bone diseases 171 23 Immobilization, exercise, and osteoporosis 179 24 Nutrition and osteoporosis 187 25 The menopause : a woman's view 193 Pt. 5 The future of diagnosis and treatment of osteoporosis 26 Future developments : risk assessment 199 27 Future therapies 209 28 How to interpret new data 213 Index 219