The new, 5th Edition of this "gold standard reference" continues to provide the most comprehensive coverage of all of the basic and clinical sciences in maternal-fetal medicine. From genetics and genetic testing...through fetal and placental growth and development...to fetal evaluation, this reference describes the diagnosis and management of every significant clinical entity involving the mother, the fetus, or both. Continues to offer unparalleled coverage of genetic disorders · both the perinatal and neonatal period · multiple gestation · preterm and post-term delivery · care of the high-risk neonate · cerebral palsy in the infant · anesthetic considerations in the complicated pregnancy · and the screening and diagnosis of congenital disorders Covers hot topics such as statistical considerations in perinatal medicine · screening and diagnosis of congenital disorders · antenatal assessment of fetal status · assessment and induction of fetal pulmonary maturity · thrombophylic disorders · and the management of depression and psychoses during pregnancy and the puerperium. Offers completely revised and updated coverage from cover to cover. Includes fresh perspectives from a wealth of new expert contributors and a new associate editor.

Ch. 1 Basic Genetics and Patterns of Inheritance 3 Ch. 2 Normal Early Development 37 Ch. 3 Amniotic Fluid Dynamics 45 Ch. 4 Multiple Gestation: The Biology of Twinning 55 Ch. 5 Biology and Physiology of the Reproductive Tract and Control of Myometrial Contraction 69 Ch. 6 Characteristics of Parturition 79 Ch. 7 The Immunology of Pregnancy 89 Ch. 8 Maternal Cardiovascular and Renal Adaptation to Pregnancy 111 Ch. 9 Endocrinology of Pregnancy 121 Ch. 10 The Breast and the Physiology of Lactation 135 Ch. 11 Maternal Nutrition 155 Ch. 12 The Puerperium 165 Ch. 13 Fetal Cardiovascular Physiology 169 Ch. 14 Fetal Breathing and Body Movements 181 Ch. 15 Placental Respiratory Gas Exchange and Fetal Oxygenation 199 Ch. 16 Fetal Lung Development 209 Ch. 17 Evidence-Based Practice in Perinatal Medicine 223 Ch. 18 Prenatal Diagnosis of Congenital Disorders 235 Ch. 19 Effects of Therapeutic, Diagnostic, and Environmental Agents and Exposure to Social and Illicit Drugs 281 Ch. 20 General Principles and Applications of Ultrasonography 315 Ch. 21 Assessment of Fetal Health 357 Ch. 22 Intrapartum Fetal Surveillance 403 Ch. 23 Fetal Acid-Base Balance 429 Ch. 24 Significance of Amniotic Fluid Meconium 441 Ch. 25 Assessment and Induction of Fetal Pulmonary Maturity 451 Ch. 26 Fetal Cardiac Arrhythmias: Diagnosis and Therapy 465 Ch. 27 Fetal Therapy: Medical and Surgical Approaches 483 Ch. 28 Intrauterine Growth Restriction 495 Ch. 29 Multiple Gestation: Clinical Characteristics and Management 513 Ch. 30 Hemolytic Disease of the Fetus and Newborn 537 Ch. 31 Nonimmune Hydrops 563 Ch. 32 Recurrent Pregnancy Loss 579 Ch. 33 Abnormal Cervical Competence 603 Ch. 34 Preterm Labor and Delivery 623 Ch. 35 Post-term Pregnancy 663 Ch. 36 Clinical Aspects of Normal and Abnormal Labor 671 Ch. 37 Placenta Previa and Abruptio Placentae 707 Ch. 38 Premature Rupture of the Membranes 723 Ch. 39 Maternal and Fetal Infectious Disorders 741 Ch. 40 Human Immunodeficiency Virus 803 Ch. 41 Cardiac Diseases 815 Ch. 42 Thromboembolic Disease 845 Ch. 43 Pregnancy-Related Hypertension 859 Ch. 44 Renal Disorders 901 Ch. 45 Intensive Care Monitoring of the Critically Ill Pregnant Patient 925 Ch. 46 Respiratory Diseases in Pregnancy 953 Ch. 47 Maternal Hematologic Disorders 975 Ch. 48 Thrombophilias in Pregnancy 1005 Ch. 49 Diabetes in Pregnancy 1023 Ch. 50 Thyroid Disease and Pregnancy 1063 Ch. 51 Other Endocrine Disorders of Pregnancy 1083 Ch. 52 Gastrointestinal Disease in Pregnancy 1109 Ch. 53 Diseases of the Liver, Biliary System, and Pancreas 1127 Ch. 54 Rheumatologic and Connective Tissue Disorders 1147 Ch. 55 Neurologic Disorders 1165 Ch. 56 Management of Depression and Psychoses during Pregnancy and the Puerperium 1193 Ch. 57 The Skin and Pregnancy 1201 Ch. 58 Pelvic Malignancies, Gestational Trophoblastic Neoplasia, and Nonpelvic Malignancies 1213 Ch. 59 Anesthetic Considerations for Complicated Pregnancies 1243 Ch. 60 Identification and Management of Problems in the High-Risk Neonate 1263 Ch. 61 Cerebral Palsy 1303 Index 1325