Optical Coherence Tomography of Ocular Diseases, Second Edition is a completely revised and updated version of this classic text. Incorporated within over 700 pages are a multitude of updated features unique to this edition including over 1,600 color images, state-of-the-art technology, and case presentations. These elements cohesively work together to successfully demonstrate the retina in normal and diseased states using the innovative Stratus OCTTM. Optical Coherence Tomography of Ocular Diseases, Second Edition is written with the clinician in mind. The text's primary objective is to illustrate the appearance of the eye in health and disease, comparing conventional clinical technologies using OCT imaging. This method introduces the clinician to the manifestations of disease as elucidated by OCT, while presenting the more familiar fundoscopic and fluorescein angiographic appearance side-by-side. Drs. Joel S. Schuman, Carmen A. Puliafito, and James G. Fujimoto, PhD together with their co-authors have collaborated to produce this comprehensive resource. OCT applications in retinal diseases, glaucoma, neuro-ophthalmology, anterior segment and a description of OCT technologies are all topics extensively covered in this new edition. An appendix is included that contains a wealth of technical information for those interested in learning more about the principles of operation of this medical diagnostic imaging technology. This text will provide a clinical reference for the retinal and glaucoma specialist that shows how to utilize and interpret OCT imaging to enhance diagnostic sensitivity and specificity as well as to enhance therapeutic decision making andmonitor the outcome of treatment. Both clinicians and scientists interested in optical imaging of the eye will find this insightful text a useful reference. Features: Over 1,600 color images. Strong focus on retina, glaucoma, and the anterior segments. Utilizes and interprets OCT imaging.

Dedication Contributors Preface Section I: Principles of Operation and Interpretation Chapter 1: Principles of Optical Coherence Tomography James G. Fujimoto, PhD; Michael R. Hee, MD, PhD; David Huang, MD, PhD; Joel S. Schuman, MD; Carmen A. Puliafito, MD; and Eric Swanson, MS Introduction How Optical Coherence Tomography Works Optical Coherence Tomography Instrumentation Summary Chapter 2 Interpretation of the Optical Coherence Tomography Image Michael R. Hee, MD, PhD; James G. Fujimoto, PhD; Tony Ko, MS; Ji Eun Lee, MD; Joel S. Schuman, MD; Jay Duker, MD; and Carmen A. Puliafito, MD Introduction Optical Coherence Tomography Image Generation and Optical Properties of Tissue Interpreting Optical Coherence Tomography Images of the Normal Retina Interpreting Optical Coherence Tomography Images of the Normal Anterior Eye Optical Coherence Tomography Scanning and Imaging Protocols Quantitative Measurements of Retinal Morphology Interpreting Optical Coherence Tomography Images of Retinal Pathologies Quality, Artifacts, and Errors in Optical Coherence Tomography Images Summary Section II: Optical Coherence Tomography in Retinal Diseases Chapter 3: Vitreoretinal Interface Disorders Elias C. Mavrofrides, MD; Adam H. Rogers, MD; Steven Truong, MD; Carmen A. Puliafito, MD; and James G. Fujimoto, PhD Idiopathic Epiretinal Membrane Vitreomacular Traction Syndrome Idiopathic Macular Hole Full-Thickness Macular Hole Lamellar Macular Hole Chapter 4: Retinal Vascular Diseases Vanessa Cruz-Villegas, MD; Carmen A. Puliafito, MD; and James G. Fujimoto, PhD Branch Retinal Artery Occlusion Central Retinal Artery Occlusion Branch Retinal Vein Occlusion Central Retinal Vein Occlusion Bilateral Idiopathic Juxtafoveal Retinal Telangiectasis Retinal Arterial Macroaneurysm Chapter 5: Diabetic Retinopathy Vanessa Cruz-Villegas, MD and Harry W. Flynn Jr, MD Nonproliferative Diabetic Retinopathy Diabetic Macular Edema Proliferative Diabetic Retinopathy Chapter 6: Central Serous Chorioretinopathy Elias C. Mavrofrides, MD; Carmen A. Puliafito, MD; and James G. Fujimoto, PhD Typical Central Serous Chorioretinopathy Chronic Central Serous Chorioretinopathy Bullous Central Serous Chorioretinopathy Laser Treatment for Central Serous Chorioretinopathy Photodynamic Therapy Treatment for Central Serous Chorioretinopathy Chapter 7: Age-Related Macular Degeneration Elias C. Mavrofrides, MD; Natalia Villate, MD; Philip J. Rosenfeld, MD; and Carmen A. Puliafito, MD Drusen Vitelliform Macular Degeneration Geographic Atrophy Choroidal Neovascularization Retinal Angiomatous Proliferation Retinal Pigment Epithelial Tear Subretinal Hemorrhage Disciform Scarring Chapter 8: Miscellaneous Macular Degenerations Elias C. Mavrofrides, MD and Carmen A. Puliafito, MD Pathologic Myopia Angioid Streaks Idiopathic Choroidal Neovascularization Central Serous Chorioretinopathy With Choroidal Neovascularization Juxtafoveal Telangiectasis With Choroidal Neovascularization Presumed Ocular Histoplasmosis Chapter 9: Chorioretinal Inflammatory Diseases Natalia Villate, MD; Elias C. Mavrofrides, MD; and Janet Davis, MD Intermediate Uveitis Idiopathic Retina Vasculitis and Neuroretinitis Multifocal Choroiditis Sarcoidosis Vogt-Koyanagi-Harada Disease Sympathetic Ophthalmia Birdshot Chorioretinopathy Toxoplasmosis Syphilitic Uveitis Cytomegalovirus Retinitis With Immune Recovery Uveitis Chapter 10: Retinal Dystrophies Vanessa Cruz-Villegas, MD; Philip J. Rosenfeld, MD; and Carmen A. Puliafito, MD Retinitis Pigmentosa Cone-Rod Dystrophy Stargardt's Disease Best's Disease Pattern Dystrophy X-Linked Juvenile Retinoschisis Chapter 11: Miscellaneous Retinal Diseases Elias C. Mavrofrides, MD; Vanessa Cruz-Villegas, MD; and Carmen A. Puliafito, MD Pseudophakic Cystoid Macular Edema Cystoid Macular Edema Associated With Glaucoma Therapy Rhegmatogenous Retinal Detachment Posterior Segment Trauma Congenital Pit of the Optic Disc Myelinated Nerve Fiber Layer Cancer-Associated Retinopathy Section III: Optical Coherence Tomography in Glaucoma, Neuro-Ophthalmology, and the Anterior Segment Chapter 12: Optical Coherence Tomography in Glaucoma Gadi Wollstein, MD; Siobahn Beaton; Adelina Paunescu, PhD; Hiroshi Ishikawa, MD; James G. Fujimoto, PhD; and Joel S. Schuman, MD Normal Eyes Structure-Function Correspondence The Utility of Imaging in Early Glaucoma Glaucoma is Global Imaging Supports Early, Questionable Visual Field Findings Imaging Discloses Functional Artifact Imaging Suggests Actual Glaucoma Damage Exceeds Visual Fields Beware Artifact Nerve Fiber Layer is Superior to Optic Nerve Head and Macula in Sensitivity to Glaucomatous Damage Abnormal Structure With Normal Function May Suggest Future Functional Loss Longitudinal Analysis Chapter 13: Optical Coherence Tomography in Neuro-Ophthalmology Thomas R. Hedges III, MD Optic Atrophy Optic Disc Swelling Anomalies Chapter 14: Corneal and Anterior Segment Optical Coherence Tomography David Huang, MD, PhD; Yan Li, MS; Sunita Radhakrishnan, MD; and Maria Regina Chalita, MD, PhD Section IV: Appendices Appendix A: Physical Principles of Optical Coherence Tomography James G. Fujimoto, PhD; David Huang, MD, PhD; Michael R. Hee, MD, PhD; Tony Ko, MS; Eric Swanson, MS; Carmen A. Puliafito, MD; and Joel S. Schuman, MD Introduction Optical Interferometry Low-Coherence Interferometry Measurement of Light Echoes Sensitivity Spatial Resolution Pixel Density and Image Acquisition Time Advances in Optical Coherence Tomography Technology Summary Appendix B: Optical Coherence Tomography Scanning and Image-Processing Protocols Ji Eun Lee, MD; Joel S. Schuman, MD; James G. Fujimoto, PhD; and Carmen A. Puliafito, MD Line Scan Protocols Circle Scan Protocols Time-Efficient or Fast Scans Image-Processing Protocols Retinal Thickness and Retinal Thickness Map Nerve Fiber Layer Optic Disc Index