The AJCC Cancer Staging Manual and Handbook, prepared by the American Joint Committee on Cancer, are used by physicians and health care professionals throughout the world to facilitate the uniform description of neoplastic diseases. Proper classification and staging allow the physician to determine treatment more appropriately, evaluate results of management more reliably, and compare worldwide statistics reported from various institutions on a local, regional, and national basis more confidently. The fully revised and updated Sixth Edition of the AJCC Cancer Staging Manual brings together all currently available information on staging of cancer at various anatomic sites and incorporates newly acquired knowledge on the etiology and pathology of cancer. As more is learned, cancer staging must adapt to accommodate new information and this revised edition provides an evidence-based staging system based upon the established tenets of TNM classification. All of the TNM staging information included in the Sixth Edition is uniform between the AJCC and the UICC (International Union Against Cancer). Organized by disease site into 48 comprehensive chapters, the Sixth Edition features much-anticipated, major revisions to the chapters on melanoma and breast cancer. Numerous new line drawings illustrate key anatomic sites throughout the text. Additional user-friendly enhancements include: * a concise summary of changes in the TNM classification since the previous edition at the start of every chapter * color-coordinated page tabs for easy access between chapters * a CD-ROM packaged with each Manual containing printable copies of each of the book's 45 Staging Forms for both individual andinstitutional use * a comprehensive index The Sixth Edition of the AJCC Cancer Staging Manual and Handbook remains the essential reference for oncologists, pathologists, surgeons, cancer registrars, and medical professionals worldwide to assure that all those taking care of cancer patients will be trained in the language of cancer staging
Preface
Brief Contents by Part
Pt. I
General Information on Cancer Staging and End-Results Reporting
1
1
Purposes and Principles of Staging
3
2
Cancer Survival Analysis
9
Pt. II
Head and Neck Sites
17
3
Lip and Oral Cavity
23
4
Pharynx (Including Base of Tongue, Soft Palate, and Uvula)
33
5
Larynx
47
6
Nasal Cavity and Paranasal Sinuses
59
7
Major Salivary Glands (Parotid, Submandibular, and Sublingual)
69
8
Thyroid
77
Pt. III
Digestive System
89
9
Esophagus
91
10
Stomach
99
11
Small Intestine
107
12
Colon and Rectum
113
13
Anal Canal
125
14
Liver (Including Intrahepatic Bile Ducts)
131
15
Gallbladder
139
16
Extrahepatic Bile Ducts
145
17
Ampulla of Vater
151
18
Exocrine Pancreas
157
Pt. IV
Thorax
165
19
Lung
167
20
Pleural Mesothelioma
179
Pt. V
Musculoskeletal Sites
185
21
Bone
187
22
Soft Tissue Sarcoma
193
Pt. VI
Skin
201
23
Carcinoma of the Skin (Excluding Eyelid, Vulva, and Penis)
203
24
Melanoma of the Skin
209
Pt. VII
Breast
221
25
Breast
223
Pt. VIII
Gynecologic Sites
241
26
Vulva
243
27
Vagina
251
28
Cervix Uteri
259
29
Corpus Uteri
267
30
Ovary
275
31
Fallopian Tube
285
32
Gestational Trophoblastic Tumors
293
Pt. IX
Genitourinary Sites
301
33
Penis
303
34
Prostate
309
35
Testis
317
36
Kidney
323
37
Renal Pelvis and Ureter
329
38
Urinary Bladder
335
39
Urethra
341
Pt. X
Ophthalmic Sites
347
40
Carcinoma of the Eyelid
349
41
Carcinoma of the Conjunctiva
355
42
Malignant Melanoma of the Conjunctiva
361
43
Malignant Melanoma of the Uvea
365
44
Retinoblastoma
371
45
Carcinoma of the Lacrimal Gland
377
46
Sarcoma of the Orbit
381
Pt. XI
Central Nervous System
385
47
Brain and Spinal Cord
387
Pt. XII
Lymphoid Neoplasms
391
48
Lymphoid Neoplasms
393
Pt. XIII
Personnel and Contributors
407
Index
417