An essential handbook, Wet Urinalysis provides up-to-date information on dipstick testing, chemical and microscopic analysis, and urine sediment. More than 200 full-color ?
Preface
vii
Acknowledgments
viii
Chapter 1
Frontline Diagnostic Urinalysis
1
Types of Urinalyses
3
Changing Times for Urinalysis
3
Clinical Objectives of Urinalysis
4
Clinical Utility of Diagnostic Wet Urinalysis
5
Limitations of Diagnostic Wet Urinalysis
6
References
8
Chapter 2
Anatomy and Physiology of the Urinary System
9
Gross Anatomy and Histology of the Kidneys
9
Anatomy and Histology of the Urinary Bladder
12
Anatomy and Histology of the Urethra
12
Four Major Processes in Urine Formation
13
Pathway of Urine Formation
13
References
14
Chapter 3
Specimen Collection, Preservation and Transportation
15
Types of Transportation and Storage of Containers
15
Noninstrumented Collection Procedures
16
Instrumented Collection Procedures
17
Chemical and Cellular Degeneration
17
Techniques Used to Minimize Degeneration
17
References
19
Chapter 4
Dipstick Urinalysis and Additional or Confirmatory Urine Chemical Testing
21
Background
21
Clinical Utility
21
Manual Procedure for Dipstick Urinalysis
22
Principles, Specificity, and Sensitivity of Dipstick Urinalysis
22
Types of Specimens for Dipstick Urinalysis
29
Sensitivity and Specificity of Urinary Reagent Test Strips
29
Confirmatory Tests and Implications
29
Clinical Significance of Positive Reactions
30
Quality Control and Quality Assurance
30
Future Trends
31
References
32
Chapter 5
Wet Microscopic Urinalysis
33
Automated and Semi-Automated Systems
33
Clinical Utility of Wet Urinoscopy
35
Laboratory Procedure
37
Reporting
37
Limitations of Wet Urine Microscopy
38
Quality Control and Quality Assurance
38
Dipstick Correlation with Wet Urinoscopy
38
Techniques, Interpretations, and Other Considerations
38
References
39
Chapter 6
Common Urine Sediment Entities
41
Background Elements
41
Hematopoietic Cells
41
Urinary Epithelial Cells
42
Urinary Casts
43
Urinary Microorganisms
45
Parasites
45
Urinary Concretions
45
Urinary Crystals
45
Secretions
48
Chapter 7
Normal Wet Urinalysis Findings
49
Physical and Chemical Examination of Urine
49
Urine Sediment Examination
49
Hematopoietic Cells in "Normal" Urine
50
Epithelial Cells
50
Casts in "Normal" Urine
51
Microorganisms in "Normal" Urine
51
Crystals in "Normal" Urine
51
References
51
Chapter 8
Abnormal Wet Urinalysis Findings
53
Physical and Chemical Examination of Urine
53
Urine Sediment Examination
54
Hemapoietic Cells in "Abnormal" Urine
54
Epithelial Cells in "Abnormal" Urine
55
Microorganisms Found in "Abnormal" Urine
56
Crystals (Crystalluria)
57
Concretions and Secretions
58
Lipiduria
58
Implications of "Abnormal" Wet Urinalysis Findings
58
Chapter 9
Indeterminate Wet Urinalysis Findings
61
Approaches to "Indeterminate" Urine Sediment Entities
62
Conclusion
65
Chapter 10
Quality Control and Quality Assurance Guidelines for the Wet Urinalysis Laboratory
67
Quality Control and Assurance Guidelines
67
Conclusion
72
References
72
Glossary
73
Appendices
81
Appendix 1
Urinary System Disorders: Algorithms and Correlations
81
Appendix 2
Plates
101
Index
121