This succinct text emphasizes diagnostic issues and pathophysiology to help nephrology fellows and practitioners quickly identify and treat kidney disease. Providing concise clinical summaries of 64 renal disorders, each chapter addresses the pathophysiology, diagnosis, and management of a specific problem to help the reader make effective clinical decisions.

Preface I Acid-Base and Electrolyte Disorders 1 Hyponatremia 3 2 Hypernatremia and Polyuric States 18 3 Diuretics: Uses and Complications 30 4 Metabolic Acidosis 42 5 Metabolic Alkalosis 64 6 Disorders of Plasma Potassium 74 7 Disorders of Calcium, Phosphorus, and Magnesium 96 II Hypertension 8 Essential Hypertension 123 9 Resistant Hypertension 150 10 Secondary Hypertension 155 11 Hypertensive Urgencies and Emergencies 168 III Diagnostic Approach to the Patient with Renal Disease 12 The Urinalysis 179 13 Creatinine and Glomerular Filtration Rate: Uses and Limitations 185 14 Renal Function in Neonates, Infants, and Children 191 15 Isolated Proteinuria and Hematuria 193 IV Acute Renal Failure 16 Differential Diagnosis of Acute Renal Failure 203 17 Prerenal Disease 207 18 Acute Tubular Necrosis 220 19 Acute Drug-Induced Interstitial Nephritis 246 V Glomerular Diseases 20 Differential Diagnosis of Glomerular Disease 253 21 Minimal Change Disease 266 22 Focal Glomerulosclerosis 275 23 Membranous Nephropathy 286 24 Diabetic Nephropathy 296 25 Amyloidosis and Light-Chain Deposition Disease 309 26 Fibrillary Glomerulonephritis 315 27 IgA Nephropathy 317 28 Hereditary Nephritis and Thin-Basement-Membrane Disease 324 29 Postinfectious Glomerulonephritis 329 30 Membranoproliferative Glomerulonephritis 334 31 Lupus Nephritis 340 32 Rapidly Progressive Glomerulonephritis 352 VI Vascular Diseases of the Kidney 33 Introduction to Renal Vasculitides 361 34 Antineutrophil Cytoplasmic Antibodies in Renal Disease 363 35 Wegener's Granulomatosis 366 36 Polyarteritis Nodosa and Churg-Strauss Syndrome 371 37 Hypersensitivity Vasculitis 374 38 Renal Complications of Scleroderma 380 39 Hemolytic-Uremic Syndromes 383 40 Renal Complications of Pregnancy 392 41 Thromboembolic and Atheroembolic Diseases 405 42 Renal Cortical Necrosis 409 43 Sickle Cell Nephropathy 411 44 Radiation Nephritis 416 VII Tubulointerstitial Disease 45 Chronic Pyelonephritis and Reflux Nephropathy 419 46 Uric Acid Kidney Disease and Lead Nephropathy 424 47 Analgesic Abuse Nephropathy and Papillary Necrosis 428 48 Myeloma Kidney 432 49 Hypercalcemic Nephropathy and Sarcoidosis 438 50 Cystic Renal Diseases 445 51 Nephrolithiasis 461 52 Urinary Tract Obstruction 476 VIII Chronic Renal Failure 53 Prevention of Chronic Renal Failure 485 54 Signs and Symptoms of Uremia 497 IX Dialysis and Transplantation 55 Hemodialysis 527 56 Peritoneal Dialysis 539 57 Management of Drug Intoxications 551 58 Renal Transplantation 555 59 Special Problems in Renal Transplantation 573 Index 579