This book, which includes the first fourteen chapters of the acclaimed monograph DNA Replication in Eukaryotic Cells, is a broad account of the basic principles of DNA replication and related functions such as DNA repair and protein phosphorylation. It also includes a newly commissioned chapter in which the editor, Mel DePamphilis, provides a review of the most recent advances in understanding the complex gene and protein interactions that underpin this essential cellular function. DNA Replication in Eukaryotic Cells has been acclaimed as ?...an absolute must for anyone working in the DNA replication field? (Trends in Cell Biology), ?...highly significant addition to the replication literature? (Trends in Biochemical Sciences) and ?...an invaluable addition for libraries...the first place to stop for anyone wishing to enter the eukaryotic replication field? (The Quarterly Review of Biology). This abridged edition is ideal for graduate students or established investigators who need a complete and timely introduction to this rapidly advancing field of research.

Preface to Concepts in Eukaryotic DNA Replication Preface to DNA Replication in Eukaryotic Cells Acknowledgments Chapter 1: Mechanisms for Replicating DNA G.S. Brush and T.J. Kelly Chapter 2: Origins of DNA Replication M.L. DePamphilis Chapter 3: Roles of Transcription Factors in DNA Replication P.C. van der Vliet Chapter 4: Roles of Nuclear Structure in DNA Replication R. Laskey and M. Madine Chapter 5: Mechanisms for Priming DNA Synthesis M. Salas, J.T. Miller, J. Leis, and M.L. DePamphilis Chapter 6: Mechanisms for Completing DNA Replication D. Bastia and B.K. Mohanty Chapter 7: Fidelity of DNA Replication J.D. Roberts and T.A. Kunkel Chapter 8: DNA Excision Repair Pathways E.C. Friedberg and R.D. Wood Chapter 9: Chromatin Structure and DNA Replication: Implications for Transcriptional Activity A.P. Wolffe Chapter 10: Roles of Phosphorylation in DNA Replication K. Weisshart and E. Fanning Chapter 11: Control of S Phase K. Nasmyth Chapter 12: Temporal Order of DNA Replication I. Simon and H. Cedar Chapter 13: Changes in DNA Replication during Animal Development J.L. Carminati and T.L. Orr-Weaver Chapter 14: Comparison of DNA Replication in Cells from Prokarya and Eukarya B. Stillman Chapter 15: DNA Replication in Eukaryotic Cells: 1996 to 1998 M.L. DePamphilis Index